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The role of prostaglandins


However, in most cases, spasmodic menstrual pains are caused by hormone-like substances produced in the body. These are so-called prostaglandins. Prostaglandins cause uterine contractions not only during menstruation, but also during labor. “These cuts that you feel like pain serve an important purpose,” explains Dr. Rabin. “During menstruation, part of the uterine lining is shed. The spasms of blood vessels caused by prostaglandins lead to the separation of tissues. The blood vessels in the uterus contract and expand, and prostaglandins are produced during this time. They support the process. In the end, the dilating vessels begin to bleed, and this leads to the separation of the surface layer of the uterine mucosa. "
This process does not stop. “On the first day, when the bleeding is abundant, the spasms support the expansion of the blood vessels at such a level that the mucous membrane comes off, preventing bleeding,” says Dr. Rabin. As the uterus contracts, the blood and mucous tissues are brought out. ”
Prostaglandins are produced in all. Why do some women experience more pain than others? “Expansion and contraction of vessels occurs in all, continues Dr. Rabin. But the pain threshold for different people is different. Some do not feel spasmodic pains at all. But a number of women produce more prostaglandins, or their receptors bind prostaglandins in such a way that their action is enhanced. ”
Usually drugs like ibuprofen and anaprox relieve pain caused by spasms because they are antiprostaglandins, that is, they block the production of prostaglandins or prevent their binding to receptors. These medicines also reduce diarrhea and nausea, and sometimes hot flashes that some women have.
Your doctor may have to experiment before he finds the right medicine for you. Mimi Cowan first took free-selling ibuprofen and prescription anaprox and received some relief. When the doctor prescribed her another antiprostaglandin to relieve pain in the neck, Mimi discovered that he also relieved her of spasmodic pains before and during menstruation. "And in the future, he continued to prescribe this remedy for me precisely to relieve menstrual pain," she says.
Some women help physical exercises. “Physical exercises contribute to a better supply of oxygen to tissues, therefore, toxins and body waste are eliminated more quickly,” says Dr. Rabin.
There are a number of non-traditional methods, not related to the use of drugs, which help some. This is meditation, drinking eight to ten glasses of water a day, going on a diet low in fat and sugar, with a very small amount of alcohol and a total absence of caffeine, a diet that many clinicians find useful in premenstrual syndrome.