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Antiadrenergic drugs

Blocking the transmission of nervous excitation in the area of ​​adrenoreceptors can be done in different ways:
a) blocking adrenoreceptors, i.e., disrupting the interaction of the mediator with adrenoreactive systems without disrupting the process of formation of the mediator and its isolation from the nerve endings; pharmacological substances that have this effect, called adrenoblokiruyuschimi substances (adrenoblockers, or adrenolytics);
b) violation of the accumulation and release of the mediator by nerve endings; this effect is carried out by sympatholytic substances;
c) violation of the mediator formation process.
In contrast to ganglioblokiruyuschikh substances antiadrenergicheskie substances interrupt the conduct of efferent nerve excitation, acting on postganglionic synapses, without affecting the transfer of excitation in the ganglia.
Antiadrenergic substances are widely used as vasodilators, antianginal, antihypertensive drugs.