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Drugs that affect the muscles of the uterus (uterine products)

Until recent years, predominantly agents that increase the tone and enhance the contractile activity of the myometrium (ergot preparations, oxytocin, etc.) were referred to uterine preparations. If necessary, to reduce the contractile activity and tone of the uterus, sedatives, anesthetics (nitrous oxide, ether, fluorothane, etc.), antispasmodics and anticholinergics were used.
In recent years, the arsenal of uterine products has expanded significantly. New highly active drugs that stimulate the myometrium (from the prostaglandin group) and new drugs that inhibit uterine contractile activity (mainly from the group Ab -drenostimulyatorov), called "tocolytics" (from tocus-genera), have appeared.
Thus, at present, uterine drugs are divided into 2 main groups: a) agents that stimulate the muscles of the uterus (oxytocytes), and b) agents that lower the tone and contractile activity of the uterus (tocolytics).
The first group includes oxytocin, ergot drugs, prostaglandins, etc. Recently, b-adrenoceptor blocking agents have also been used to stimulate labor activity (see Inderal).
Tocolytics include mainly drugs from the group
A b -adrenostimulyatorov (partusisten, fenoterol, sulbupart, ritodrin, etc.).
Group Means affecting the muscles of the uterus (uterine means) include the following subgroups: